Regulation of Inositol 1,4,5-Trisphosphate Receptors by cAMP Independent of cAMP-dependent Protein Kinase

In HEK cells stably expressing type 1 receptors for parathyroid hormone (PTH), PTH causes a sensitization of inositol 1,4,5-trisphosphate receptors (IP(3)R) to IP(3) that is entirely mediated by cAMP and requires cAMP to pass directly from type 6 adenylyl cyclase (AC6) to IP(3)R2. Using DT40 cells e...

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Détails bibliographiques
Auteurs principaux: Tovey, Stephen C., Dedos, Skarlatos G., Rahman, Taufiq, Taylor, Emily J. A., Pantazaka, Evangelia, Taylor, Colin W.
Format: Artigo
Langue:Inglês
Publié: American Society for Biochemistry and Molecular Biology 2010
Sujets:
Signal Transduction
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2857138/
https://ncbi.nlm.nih.gov/pubmed/20189985
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M109.096016
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