Parathyroid hormone increases the sensitivity of inositol trisphosphate receptors by a mechanism that is independent of cyclic AMP

1. In fura 2-loaded HEK-293 cells stably expressing human type 1 parathyroid hormone (PTH) receptors, PTH potentiated the Ca(2+) mobilization evoked by carbachol by >4 fold without itself increasing the intracellular [Ca(2+)]. 2. PTH potentiated the Ca(2+) release evoked by a cell-permeant analog...

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Main Authors: Tovey, Stephen C, Goraya, Tasmina A, Taylor, Colin W
Format: Artigo
Jezik:Inglês
Izdano: 2003
Teme:
Papers
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC1573637/
https://ncbi.nlm.nih.gov/pubmed/12522076
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0705011
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