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Parathyroid hormone increases the sensitivity of inositol trisphosphate receptors by a mechanism that is independent of cyclic AMP
1. In fura 2-loaded HEK-293 cells stably expressing human type 1 parathyroid hormone (PTH) receptors, PTH potentiated the Ca(2+) mobilization evoked by carbachol by >4 fold without itself increasing the intracellular [Ca(2+)]. 2. PTH potentiated the Ca(2+) release evoked by a cell-permeant analog...
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| Autori principali: | , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
2003
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1573637/ https://ncbi.nlm.nih.gov/pubmed/12522076 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0705011 |
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