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Upregulation of HERV-K is Linked to Immunity and Inflammation in Pulmonary Arterial Hypertension

BACKGROUND: Immune dysregulation has been linked to occlusive vascular remodeling in pulmonary arterial hypertension (PAH) that is hereditary, idiopathic or associated with other conditions. Circulating autoantibodies, lung perivascular lymphoid tissue and elevated cytokines have been related to PAH...

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Detalhes bibliográficos
Publicado no:Circulation
Main Authors: Saito, Toshie, Miyagawa, Kazuya, Chen, Shih-Yu, Tamosiuniene, Rasa, Wang, Lingli, Sharpe, Orr, Samayoa, Erik, Harada, Daisuke, Moonen, Jan-Renier A. J., Cao, Aiqin, Chen, Pin-I, Hennigs, Jan K., Gu, Mingxia, Li, Caiyun G., Leib, Ryan D., Li, Dan, Adams, Christopher M., del Rosario, Patricia A., Bill, Matthew, Haddad, Francois, Montoya, Jose G., Robinson, William H., Fantl, Wendy J., Nolan, Garry P., Zamanian, Roham T., Nicolls, Mark R., Chiu, Charles Y., Ariza, Maria E., Rabinovitch, Marlene
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5685911/
https://ncbi.nlm.nih.gov/pubmed/28935667
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/CIRCULATIONAHA.117.027589
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