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E3 ligase mahogunin (MGRN1) influences amyloid precursor protein maturation and secretion
Altered processing of the Amyloid Precursor Protein (APP) is a well-recognized central pathogenic mechanism in Alzheimer's Disease (AD), and regulation of APP processing is a major focus of research in the AD field. However, how age-associated cellular and molecular changes contribute to change...
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| Pubblicato in: | Oncotarget |
|---|---|
| Autori principali: | , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Impact Journals LLC
2017
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5685682/ https://ncbi.nlm.nih.gov/pubmed/29163761 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.20143 |
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