Mahogunin Ring Finger-1 (MGRN1) E3 Ubiquitin Ligase Inhibits Signaling from Melanocortin Receptor by Competition with Gα(s)

Mahogunin ring finger-1 (MGRN1) is a RING domain-containing ubiquitin ligase mutated in mahoganoid, a mouse mutation causing coat color darkening, congenital heart defects, high embryonic lethality, and spongiform neurodegeneration. The melanocortin hormones regulate pigmentation, cortisol productio...

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Detalhes bibliográficos
Main Authors: Pérez-Oliva, Ana B., Olivares, Concepción, Jiménez-Cervantes, Celia, García-Borrón, José C.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2009
Assuntos:
Mechanisms of Signal Transduction
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2797242/
https://ncbi.nlm.nih.gov/pubmed/19737927
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M109.028100
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