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Hotspots of Age-Related Protein Degradation. The Importance of Neighbouring Residues for the Formation of Non-Disulfide Crosslinks derived from Cysteine
Over time, the long-lived proteins that are present throughout the human body deteriorate. Typically, they become racemised, truncated and covalently crosslinked. One reaction responsible for age-related protein crosslinking in the lens was elucidated recently and shown to involve spontaneous format...
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| Pubblicato in: | Biochem J |
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| Autori principali: | , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
2017
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5685506/ https://ncbi.nlm.nih.gov/pubmed/28592682 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BCJ20170268 |
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