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Challenges and opportunities in the high-resolution cryo-EM visualization of microtubules and their binding partners

As non-crystallizable polymers, microtubules have been the target of cryo-electron microscopy (cryo-EM) studies since the technique was first established. Over the years, image processing strategies have been developed that take care of the unique, pseudo-helical symmetry of the microtubule. With re...

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Bibliografiske detaljer
Udgivet i:Curr Opin Struct Biol
Main Authors: Nogales, Eva, Kellogg, Elizabeth H.
Format: Artigo
Sprog:Inglês
Udgivet: 2017
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5683913/
https://ncbi.nlm.nih.gov/pubmed/28628789
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.sbi.2017.06.003
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