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Near-atomic cryo-EM structure of PRC1 bound to the microtubule

Proteins that associate with microtubules (MTs) are crucial to generate MT arrays and establish different cellular architectures. One example is PRC1 (protein regulator of cytokinesis 1), which cross-links antiparallel MTs and is essential for the completion of mitosis and cytokinesis. Here we descr...

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Dettagli Bibliografici
Pubblicato in:Proc Natl Acad Sci U S A
Autori principali: Kellogg, Elizabeth H., Howes, Stuart, Ti, Shih-Chieh, Ramírez-Aportela, Erney, Kapoor, Tarun M., Chacón, Pablo, Nogales, Eva
Natura: Artigo
Lingua:Inglês
Pubblicazione: National Academy of Sciences 2016
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5003279/
https://ncbi.nlm.nih.gov/pubmed/27493215
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1609903113
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