Structural differences between yeast and mammalian microtubules revealed by cryo-EM

Microtubules are polymers of αβ-tubulin heterodimers essential for all eukaryotes. Despite sequence conservation, there are significant structural differences between microtubules assembled in vitro from mammalian or budding yeast tubulin. Yeast MTs were not observed to undergo compaction at the int...

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Bibliographic Details
Published in:J Cell Biol
Main Authors: Howes, Stuart C., Geyer, Elisabeth A., LaFrance, Benjamin, Zhang, Rui, Kellogg, Elizabeth H., Westermann, Stefan, Rice, Luke M., Nogales, Eva
Format: Artigo
Language:Inglês
Published: The Rockefeller University Press 2017
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Research Articles
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5584162/
https://ncbi.nlm.nih.gov/pubmed/28652389
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.201612195
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