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Separating the effects of nucleotide and EB binding on microtubule structure

Microtubules (MTs) are polymers assembled from αβ-tubulin heterodimers that display the hallmark behavior of dynamic instability. MT dynamics are driven by GTP hydrolysis within the MT lattice, and are highly regulated by a number of MT-associated proteins (MAPs). How MAPs affect MTs is still not fu...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Main Authors: Zhang, Rui, LaFrance, Benjamin, Nogales, Eva
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6142192/
https://ncbi.nlm.nih.gov/pubmed/29915050
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1802637115
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