Near-atomic cryo-EM structure of PRC1 bound to the microtubule

Proteins that associate with microtubules (MTs) are crucial to generate MT arrays and establish different cellular architectures. One example is PRC1 (protein regulator of cytokinesis 1), which cross-links antiparallel MTs and is essential for the completion of mitosis and cytokinesis. Here we descr...

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Bibliographic Details
Published in:Proc Natl Acad Sci U S A
Main Authors: Kellogg, Elizabeth H., Howes, Stuart, Ti, Shih-Chieh, Ramírez-Aportela, Erney, Kapoor, Tarun M., Chacón, Pablo, Nogales, Eva
Format: Artigo
Language:Inglês
Published: National Academy of Sciences 2016
Subjects:
Biological Sciences
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5003279/
https://ncbi.nlm.nih.gov/pubmed/27493215
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1609903113
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