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Cryo-EM in the study of challenging systems: the human transcription pre-initiation complex: Challenges studying the human PIC by cryo-EM
Single particle cryo-Electron Microscopy (cryo-EM) is a technique that allows the structural characterization of macromolecules without the need for crystallization. For certain type of samples that are ideally suited for cryo-EM studies it has been possible to reach high-resolution structures follo...
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| Опубликовано в: : | Curr Opin Struct Biol |
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| Главные авторы: | , , |
| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
2016
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5161697/ https://ncbi.nlm.nih.gov/pubmed/27689812 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.sbi.2016.09.009 |
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