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Structure of promoter-bound TFIID and insight into human PIC assembly

The general transcription factor IID (TFIID) plays a central role in the initiation of RNA polymerase II-dependent transcription by nucleating pre-initiation complex (PIC) assembly at the core promoter. TFIID comprises the TATA-binding protein (TBP) and 13 TBP-associated factors (TAF1-13), which spe...

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Detalhes bibliográficos
Publicado no:Nature
Main Authors: Louder, Robert K., He, Yuan, López-Blanco, José Ramón, Fang, Jie, Chacón, Pablo, Nogales, Eva
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4856295/
https://ncbi.nlm.nih.gov/pubmed/27007846
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature17394
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