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Structure of promoter-bound TFIID and insight into human PIC assembly
The general transcription factor IID (TFIID) plays a central role in the initiation of RNA polymerase II-dependent transcription by nucleating pre-initiation complex (PIC) assembly at the core promoter. TFIID comprises the TATA-binding protein (TBP) and 13 TBP-associated factors (TAF1-13), which spe...
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Gepubliceerd in: | Nature |
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Hoofdauteurs: | , , , , , |
Formaat: | Artigo |
Taal: | Inglês |
Gepubliceerd in: |
2016
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Onderwerpen: | |
Online toegang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4856295/ https://ncbi.nlm.nih.gov/pubmed/27007846 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature17394 |
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