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Structure of human TFIID and mechanism of TBP loading onto promoter DNA
The general transcription factor IID (TFIID) is a critical component of the eukaryotic transcription preinitiation complex (PIC) and is responsible for recognizing the core promoter DNA and initiating PIC assembly. We used cryo-electron microscopy (cryo-EM), chemical crosslinking-mass spectrometry (...
Gorde:
| Argitaratua izan da: | Science |
|---|---|
| Egile Nagusiak: | , , , , , , , , , |
| Formatua: | Artigo |
| Hizkuntza: | Inglês |
| Argitaratua: |
2018
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| Gaiak: | |
| Sarrera elektronikoa: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6446905/ https://ncbi.nlm.nih.gov/pubmed/30442764 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/science.aau8872 |
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