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Towards a Mechanistic Understanding of Core Promoter Recognition from Cryo-EM Studies of Human TFIID

TFIID is a critical component of the eukaryotic transcription pre-initiation complex (PIC) required for the recruitment of RNA Pol II to the start site of protein-coding genes. Within the PIC, TFIID’s role is to recognize and bind core promoter sequences and recruit the rest of the PIC components. D...

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Bibliografiset tiedot
Julkaisussa:Curr Opin Struct Biol
Päätekijät: Nogales, Eva, Patel, Avinash B., Louder, Robert K.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: 2017
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC5723225/
https://ncbi.nlm.nih.gov/pubmed/28624568
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.sbi.2017.05.015
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