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High-resolution cryo-EM structures of TFIIH and their functional implications
Eukaryotic transcription factor IIH (TFIIH) is a 500 kDa-multiprotein complex that harbors two SF2-family DNA-dependent ATPase/helicase subunits and the kinase activity of Cyclin-dependent kinase 7. TFIIH serves as a general transcription factor for transcription initiation by eukaryotic RNA polymer...
Sparad:
| I publikationen: | Curr Opin Struct Biol |
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| Huvudupphovsmän: | , |
| Materialtyp: | Artigo |
| Språk: | Inglês |
| Publicerad: |
2019
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| Ämnen: | |
| Länkar: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6951423/ https://ncbi.nlm.nih.gov/pubmed/31600675 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.sbi.2019.08.002 |
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