Llwytho...

High-resolution cryo-EM structures of TFIIH and their functional implications

Eukaryotic transcription factor IIH (TFIIH) is a 500 kDa-multiprotein complex that harbors two SF2-family DNA-dependent ATPase/helicase subunits and the kinase activity of Cyclin-dependent kinase 7. TFIIH serves as a general transcription factor for transcription initiation by eukaryotic RNA polymer...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Curr Opin Struct Biol
Prif Awduron: Nogales, Eva, Greber, Basil J
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2019
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC6951423/
https://ncbi.nlm.nih.gov/pubmed/31600675
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.sbi.2019.08.002
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