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53BP1 and BRCA1 control pathway choice for stalled replication restart

The cellular pathways that restart stalled replication forks are essential for genome stability and tumor prevention. However, how many of these pathways exist in cells and how these pathways are selectively activated remain unclear. Here, we describe two major fork restart pathways, and demonstrate...

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Detalles Bibliográficos
Publicado en:eLife
Main Authors: Xu, Yixi, Ning, Shaokai, Wei, Zheng, Xu, Ran, Xu, Xinlin, Xing, Mengtan, Guo, Rong, Xu, Dongyi
Formato: Artigo
Idioma:Inglês
Publicado: eLife Sciences Publications, Ltd 2017
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5683755/
https://ncbi.nlm.nih.gov/pubmed/29106372
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.30523
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