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53BP1 and BRCA1 control pathway choice for stalled replication restart

The cellular pathways that restart stalled replication forks are essential for genome stability and tumor prevention. However, how many of these pathways exist in cells and how these pathways are selectively activated remain unclear. Here, we describe two major fork restart pathways, and demonstrate...

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Bibliografski detalji
Izdano u:eLife
Glavni autori: Xu, Yixi, Ning, Shaokai, Wei, Zheng, Xu, Ran, Xu, Xinlin, Xing, Mengtan, Guo, Rong, Xu, Dongyi
Format: Artigo
Jezik:Inglês
Izdano: eLife Sciences Publications, Ltd 2017
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5683755/
https://ncbi.nlm.nih.gov/pubmed/29106372
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.30523
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