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53BP1 and BRCA1 control pathway choice for stalled replication restart

The cellular pathways that restart stalled replication forks are essential for genome stability and tumor prevention. However, how many of these pathways exist in cells and how these pathways are selectively activated remain unclear. Here, we describe two major fork restart pathways, and demonstrate...

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Detalhes bibliográficos
Publicado no:eLife
Main Authors: Xu, Yixi, Ning, Shaokai, Wei, Zheng, Xu, Ran, Xu, Xinlin, Xing, Mengtan, Guo, Rong, Xu, Dongyi
Formato: Artigo
Idioma:Inglês
Publicado em: eLife Sciences Publications, Ltd 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5683755/
https://ncbi.nlm.nih.gov/pubmed/29106372
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.30523
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