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53BP1, BRCA1, and the Choice between Recombination and End Joining at DNA Double-Strand Breaks
When DNA double-strand breaks occur, the cell cycle stage has a major influence on the choice of the repair pathway employed. Specifically, nonhomologous end joining is the predominant mechanism used in the G(1) phase of the cell cycle, while homologous recombination becomes fully activated in S pha...
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| Hauptverfasser: | , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
American Society for Microbiology
2014
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3993578/ https://ncbi.nlm.nih.gov/pubmed/24469398 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.01639-13 |
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