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Replicated chromatin curtails 53BP1 recruitment in BRCA1-proficient and BRCA1-deficient cells

DNA double-strand breaks can be repaired by non-homologous end-joining or homologous recombination. Which pathway is used depends on the balance between the tumor suppressors 53BP1 and BRCA1 and on the availability of an undamaged template DNA for homology-directed repair. How cells switch from a 53...

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Detaylı Bibliyografya
Yayımlandı:Life Sci Alliance
Asıl Yazarlar: Michelena, Jone, Pellegrino, Stefania, Spegg, Vincent, Altmeyer, Matthias
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Life Science Alliance LLC 2021
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC8046418/
https://ncbi.nlm.nih.gov/pubmed/33811064
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.26508/lsa.202101023
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