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Resistance mechanisms to genetic suppression of mutant NRAS in melanoma
Targeted therapies have revolutionized cancer care but the development of resistance remains a challenge in the clinic. To identify rational targets for combination strategies, we used an established melanoma mouse model and selected for resistant tumors following genetic suppression of NRAS express...
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| Veröffentlicht in: | Melanoma Res |
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| Hauptverfasser: | , , , , , , , , , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2017
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5683096/ https://ncbi.nlm.nih.gov/pubmed/29076949 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/CMR.0000000000000403 |
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