Phosphoproteomic analysis of basal and therapy-induced adaptive signaling networks in BRAF and NRAS mutant melanoma

Basal and kinase inhibitor-driven adaptive signaling has been examined in a panel of melanoma cell lines using phosphoproteomics in conjunction with pathway analysis. A considerable divergence in the spectrum of tyrosine-phosphorylated peptides was noted at the cell line level. The unification of ge...

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Kaydedildi:
Detaylı Bibliyografya
Yayımlandı:Proteomics
Asıl Yazarlar: Fedorenko, Inna V., Fang, Bin, Munko, A. Cecelia, Gibney, Geoffrey T., Koomen, John M., Smalley, Keiran S.M.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2014
Konular:
Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC4389901/
https://ncbi.nlm.nih.gov/pubmed/25339196
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/pmic.201400200
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