DNA methylation regulates TMEM16A/ANO1 expression through multiple CpG islands in head and neck squamous cell carcinoma

ANO1 is a calcium-activated chloride channel that is frequently overexpressed in head and neck squamous cell carcinoma (HNSCC) and other cancers. While ANO1 expression negatively correlates with survival in several cancers, its epigenetic regulation is poorly understood. We analyzed HNSCC samples fr...

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Bibliografski detalji
Izdano u:Sci Rep
Glavni autori: Finegersh, Andrey, Kulich, Scott, Guo, Theresa, Favorov, Alexander V., Fertig, Elana J., Danilova, Ludmila V., Gaykalova, Daria A., Califano, Joseph A., Duvvuri, Umamaheswar
Format: Artigo
Jezik:Inglês
Izdano: Nature Publishing Group UK 2017
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Article
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5680248/
https://ncbi.nlm.nih.gov/pubmed/29123240
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-15634-9
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