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DNA methylation regulates TMEM16A/ANO1 expression through multiple CpG islands in head and neck squamous cell carcinoma

ANO1 is a calcium-activated chloride channel that is frequently overexpressed in head and neck squamous cell carcinoma (HNSCC) and other cancers. While ANO1 expression negatively correlates with survival in several cancers, its epigenetic regulation is poorly understood. We analyzed HNSCC samples fr...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Finegersh, Andrey, Kulich, Scott, Guo, Theresa, Favorov, Alexander V., Fertig, Elana J., Danilova, Ludmila V., Gaykalova, Daria A., Califano, Joseph A., Duvvuri, Umamaheswar
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2017
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5680248/
https://ncbi.nlm.nih.gov/pubmed/29123240
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-15634-9
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