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Structural basis of small molecule ATPase inhibition of a human mitotic kinesin motor protein
Kinesin microtubule motor proteins play essential roles in division, including attaching chromosomes to spindles and crosslinking microtubules for spindle assembly. Human kinesin-14 KIFC1 is unique in that cancer cells with amplified centrosomes are dependent on the motor for viable division because...
保存先:
| 出版年: | Sci Rep |
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| 主要な著者: | , , , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
Nature Publishing Group UK
2017
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5680195/ https://ncbi.nlm.nih.gov/pubmed/29123223 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-14754-6 |
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