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Structural basis for the assembly of the mitotic motor Kinesin-5 into bipolar tetramers
Chromosome segregation during mitosis depends upon Kinesin-5 motors, which display a conserved, bipolar homotetrameric organization consisting of two motor dimers at opposite ends of a central rod. Kinesin-5 motors crosslink adjacent microtubules to drive or constrain their sliding apart, but the st...
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Glavni autori: | , , , |
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Format: | Artigo |
Jezik: | Inglês |
Izdano: |
eLife Sciences Publications, Ltd
2014
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Teme: | |
Online pristup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3978770/ https://ncbi.nlm.nih.gov/pubmed/24714498 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.02217 |
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