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Force generation by kinesin and myosin cytoskeletal motor proteins
Kinesins and myosins hydrolyze ATP, producing force that drives spindle assembly, vesicle transport and muscle contraction. How do motors do this? Here we discuss mechanisms of motor force transduction, based on their mechanochemical cycles and conformational changes observed in crystal structures....
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| Main Authors: | , |
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| Format: | Artigo |
| Language: | Inglês |
| Published: |
The Company of Biologists
2013
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3603507/ https://ncbi.nlm.nih.gov/pubmed/23487037 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/jcs.103911 |
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