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Force generation by kinesin and myosin cytoskeletal motor proteins

Kinesins and myosins hydrolyze ATP, producing force that drives spindle assembly, vesicle transport and muscle contraction. How do motors do this? Here we discuss mechanisms of motor force transduction, based on their mechanochemical cycles and conformational changes observed in crystal structures....

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Detalhes bibliográficos
Main Authors: Kull, F. Jon, Endow, Sharyn A.
Formato: Artigo
Idioma:Inglês
Publicado em: The Company of Biologists 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3603507/
https://ncbi.nlm.nih.gov/pubmed/23487037
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/jcs.103911
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