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Modified metformin as a more potent anticancer drug: Mitochondrial inhibition, redox signaling, antiproliferative effects and future EPR studies

Metformin, one of the most widely prescribed antidiabetic drugs in the world is being repurposed as a potential drug in cancer treatment. Epidemiological studies suggest that metformin exerts anticancer effects in diabetic patients with pancreatic cancer. However, at typical antidiabetic doses the b...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Julkaisussa:Cell Biochem Biophys
Päätekijät: Kalyanaraman, Balaraman, Cheng, Gang, Hardy, Micael, Ouari, Olivier, Sikora, Adam, Zielonka, Jacek, Dwinell, Michael B.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: 2017
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC5680142/
https://ncbi.nlm.nih.gov/pubmed/28429253
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s12013-017-0796-3
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