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Mitochondria-targeted metformins: anti-tumour and redox signalling mechanisms

Reports suggest that metformin exerts anti-cancer effects in diabetic individuals with pancreatic cancer. Thus, metformin is currently being repurposed as a potential drug in cancer treatment. Studies indicate that potent metformin analogues are required in cancer treatment because of the low bioava...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Interface Focus
Hauptverfasser: Kalyanaraman, Balaraman, Cheng, Gang, Hardy, Micael, Ouari, Olivier, Sikora, Adam, Zielonka, Jacek, Dwinell, Michael
Format: Artigo
Sprache:Inglês
Veröffentlicht: The Royal Society 2017
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5311906/
https://ncbi.nlm.nih.gov/pubmed/28382202
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1098/rsfs.2016.0109
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