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Teaching the basics of reactive oxygen species and their relevance to cancer biology: Mitochondrial reactive oxygen species detection, redox signaling, and targeted therapies

Reactive oxygen species (ROS) have been implicated in tumorigenesis (tumor initiation, tumor progression, and metastasis). Of the many cellular sources of ROS generation, the mitochondria and the NADPH oxidase family of enzymes are possibly the most prevalent intracellular sources. In this article,...

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Detalhes bibliográficos
Publicado no:Redox Biol
Main Authors: Kalyanaraman, Balaraman, Cheng, Gang, Hardy, Micael, Ouari, Olivier, Bennett, Brian, Zielonka, Jacek
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5756055/
https://ncbi.nlm.nih.gov/pubmed/29306792
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.redox.2017.12.012
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