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Teaching the basics of reactive oxygen species and their relevance to cancer biology: Mitochondrial reactive oxygen species detection, redox signaling, and targeted therapies

Reactive oxygen species (ROS) have been implicated in tumorigenesis (tumor initiation, tumor progression, and metastasis). Of the many cellular sources of ROS generation, the mitochondria and the NADPH oxidase family of enzymes are possibly the most prevalent intracellular sources. In this article,...

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Bibliografiske detaljer
Udgivet i:Redox Biol
Main Authors: Kalyanaraman, Balaraman, Cheng, Gang, Hardy, Micael, Ouari, Olivier, Bennett, Brian, Zielonka, Jacek
Format: Artigo
Sprog:Inglês
Udgivet: Elsevier 2017
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5756055/
https://ncbi.nlm.nih.gov/pubmed/29306792
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.redox.2017.12.012
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