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Teaching the basics of reactive oxygen species and their relevance to cancer biology: Mitochondrial reactive oxygen species detection, redox signaling, and targeted therapies

Reactive oxygen species (ROS) have been implicated in tumorigenesis (tumor initiation, tumor progression, and metastasis). Of the many cellular sources of ROS generation, the mitochondria and the NADPH oxidase family of enzymes are possibly the most prevalent intracellular sources. In this article,...

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Dettagli Bibliografici
Pubblicato in:Redox Biol
Autori principali: Kalyanaraman, Balaraman, Cheng, Gang, Hardy, Micael, Ouari, Olivier, Bennett, Brian, Zielonka, Jacek
Natura: Artigo
Lingua:Inglês
Pubblicazione: Elsevier 2017
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5756055/
https://ncbi.nlm.nih.gov/pubmed/29306792
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.redox.2017.12.012
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