A unique pH-dependent recognition of methylated histone H3K4 by PPS and DIDO

Protein partner of Sans-fille (PPS) and its human homolog DIDO mediate diverse chromatin activities including the regulation of stemness genes in embryonic stem cells and splicing in Drosophila. Here, we show that the PHD fingers of PPS and DIDO recognize the histone mark H3K4me3 in a pH-dependent m...

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Publicado en:Structure
Autores principales: Tencer, Adam H., Gatchalian, Jovylyn, Klein, Brianna J., Khan, Abid, Zhang, Yi, Strahl, Brian D., van Wely, Karel H.M., Kutateladze, Tatiana G.
Formato: Artigo
Lenguaje:Inglês
Publicado: 2017
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5679713/
https://ncbi.nlm.nih.gov/pubmed/28919441
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.str.2017.08.009
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