A unique pH-dependent recognition of methylated histone H3K4 by PPS and DIDO

Protein partner of Sans-fille (PPS) and its human homolog DIDO mediate diverse chromatin activities including the regulation of stemness genes in embryonic stem cells and splicing in Drosophila. Here, we show that the PHD fingers of PPS and DIDO recognize the histone mark H3K4me3 in a pH-dependent m...

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發表在:Structure
Main Authors: Tencer, Adam H., Gatchalian, Jovylyn, Klein, Brianna J., Khan, Abid, Zhang, Yi, Strahl, Brian D., van Wely, Karel H.M., Kutateladze, Tatiana G.
格式: Artigo
語言:Inglês
出版: 2017
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Article
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC5679713/
https://ncbi.nlm.nih.gov/pubmed/28919441
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.str.2017.08.009
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