A unique pH-dependent recognition of methylated histone H3K4 by PPS and DIDO

Protein partner of Sans-fille (PPS) and its human homolog DIDO mediate diverse chromatin activities including the regulation of stemness genes in embryonic stem cells and splicing in Drosophila. Here, we show that the PHD fingers of PPS and DIDO recognize the histone mark H3K4me3 in a pH-dependent m...

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Publicat a:Structure
Autors principals: Tencer, Adam H., Gatchalian, Jovylyn, Klein, Brianna J., Khan, Abid, Zhang, Yi, Strahl, Brian D., van Wely, Karel H.M., Kutateladze, Tatiana G.
Format: Artigo
Idioma:Inglês
Publicat: 2017
Matèries:
Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5679713/
https://ncbi.nlm.nih.gov/pubmed/28919441
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.str.2017.08.009
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