Structural insight into recognition of methylated histone H3K4 by Set3

The plant homeodomain (PHD) finger of Set3 binds methylated lysine 4 of histone H3 in vitro and in vivo, however precise selectivity of this domain has not been fully characterized. Here, we explore the determinants of methyllysine recognition by the PHD fingers of Set3 and its orthologs. We use X-r...

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Udgivet i:J Mol Biol
Main Authors: Gatchalian, Jovylyn, Ali, Muzaffar, Andrews, Forest H., Zhang, Yi, Barrett, Alexander S., Kutateladze, Tatiana G.
Format: Artigo
Sprog:Inglês
Udgivet: 2016
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5374059/
https://ncbi.nlm.nih.gov/pubmed/27697561
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jmb.2016.09.020
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