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Recognition of cancer mutations in histone H3K36 by epigenetic writers and readers

Histone posttranslational modifications control the organization and function of chromatin. In particular, methylation of lysine 36 in histone H3 (H3K36me) has been shown to mediate gene transcription, DNA repair, cell cycle regulation, and pre-mRNA splicing. Notably, mutations at or near this resid...

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Detalhes bibliográficos
Publicado no:Epigenetics
Main Authors: Klein, Brianna J., Krajewski, Krzysztof, Restrepo, Susana, Lewis, Peter W., Strahl, Brian D., Kutateladze, Tatiana G.
Formato: Artigo
Idioma:Inglês
Publicado em: Taylor & Francis 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6224213/
https://ncbi.nlm.nih.gov/pubmed/30045670
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/15592294.2018.1503491
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