Recognition of cancer mutations in histone H3K36 by epigenetic writers and readers

Histone posttranslational modifications control the organization and function of chromatin. In particular, methylation of lysine 36 in histone H3 (H3K36me) has been shown to mediate gene transcription, DNA repair, cell cycle regulation, and pre-mRNA splicing. Notably, mutations at or near this resid...

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Bibliografiska uppgifter
I publikationen:Epigenetics
Huvudupphovsmän: Klein, Brianna J., Krajewski, Krzysztof, Restrepo, Susana, Lewis, Peter W., Strahl, Brian D., Kutateladze, Tatiana G.
Materialtyp: Artigo
Språk:Inglês
Publicerad: Taylor & Francis 2018
Ämnen:
Review
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC6224213/
https://ncbi.nlm.nih.gov/pubmed/30045670
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/15592294.2018.1503491
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