Accessibility of the histone H3 tail in the nucleosome for binding of paired readers

Combinatorial polyvalent contacts of histone-binding domains or readers commonly mediate localization and activities of chromatin-associated proteins. A pair of readers, the PHD fingers of the protein CHD4, has been shown to bivalently recognize histone H3 tails. Here we describe a mechanism by whic...

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Publicado no:Nat Commun
Main Authors: Gatchalian, Jovylyn, Wang, Xiaodong, Ikebe, Jinzen, Cox, Khan L., Tencer, Adam H., Zhang, Yi, Burge, Nathaniel L., Di, Luo, Gibson, Matthew D., Musselman, Catherine A., Poirier, Michael G., Kono, Hidetoshi, Hayes, Jeffrey J., Kutateladze, Tatiana G.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2017
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5686127/
https://ncbi.nlm.nih.gov/pubmed/29138400
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-017-01598-x
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