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Accessibility of the histone H3 tail in the nucleosome for binding of paired readers
Combinatorial polyvalent contacts of histone-binding domains or readers commonly mediate localization and activities of chromatin-associated proteins. A pair of readers, the PHD fingers of the protein CHD4, has been shown to bivalently recognize histone H3 tails. Here we describe a mechanism by whic...
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| Udgivet i: | Nat Commun |
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| Main Authors: | , , , , , , , , , , , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Nature Publishing Group UK
2017
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5686127/ https://ncbi.nlm.nih.gov/pubmed/29138400 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-017-01598-x |
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