ICAMs support B cell interactions with T follicular helper cells and promote clonal selection

The germinal center (GC) reaction begins with a diverse and expanded group of B cell clones bearing a wide range of antibody affinities. During GC colonization, B cells engage in long-lasting interactions with T follicular helper (Tfh) cells, a process that depends on antigen uptake and antigen pres...

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Detalhes bibliográficos
Publicado no:J Exp Med
Main Authors: Zaretsky, Irina, Atrakchi, Ofir, Mazor, Roei D., Stoler-Barak, Liat, Biram, Adi, Feigelson, Sara W., Gitlin, Alexander D., Engelhardt, Britta, Shulman, Ziv
Formato: Artigo
Idioma:Inglês
Publicado em: The Rockefeller University Press 2017
Assuntos:
Research Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5679169/
https://ncbi.nlm.nih.gov/pubmed/28939548
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20171129
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