Stable contacts of naïve CD4 T cells with migratory dendritic cells are ICAM-1-dependent but dispensable for proliferation in vivo

It is unclear if naïve T cells require dendritic cell ICAMs to proliferate inside lymph nodes. To check if and when CD4 lymphocytes use ICAMs on migratory DCs, wild-type and ICAM-1 and 2 double knock out bone marrow-derived DCs pulsed with saturating levels of an OT-II transgene-specific ovalbumin-d...

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Detalles Bibliográficos
Publicado en:Cell Adh Migr
Main Authors: Kozlovski, Stav, Atrakchi, Ofir, Feigelson, Sara W, Shulman, Ziv, Alon, Ronen
Formato: Artigo
Idioma:Inglês
Publicado: Taylor & Francis 2019
Assuntos:
Short Communication
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6682365/
https://ncbi.nlm.nih.gov/pubmed/31328672
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/19336918.2019.1644857
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