A multidimensional blood stimulation assay reveals immune alterations underlying systemic juvenile idiopathic arthritis

The etiology of sporadic human chronic inflammatory diseases remains mostly unknown. To fill this gap, we developed a strategy that simultaneously integrates blood leukocyte responses to innate stimuli at the transcriptional, cellular, and secreted protein levels. When applied to systemic juvenile i...

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Vydáno v:J Exp Med
Hlavní autoři: Cepika, Alma-Martina, Banchereau, Romain, Segura, Elodie, Ohouo, Marina, Cantarel, Brandi, Goller, Kristina, Cantrell, Victoria, Ruchaud, Emily, Gatewood, Elizabeth, Nguyen, Phuong, Gu, Jinghua, Anguiano, Esperanza, Zurawski, Sandra, Baisch, Jeanine M., Punaro, Marilynn, Baldwin, Nicole, Obermoser, Gerlinde, Palucka, Karolina, Banchereau, Jacques, Amigorena, Sebastian, Pascual, Virginia
Médium: Artigo
Jazyk:Inglês
Vydáno: The Rockefeller University Press 2017
Témata:
Research Articles
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5679164/
https://ncbi.nlm.nih.gov/pubmed/28935693
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20170412
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