Interferon priming is necessary but not sufficient to turn on a migratory dendritic cell program in lupus monocytes

Blood monocytes from children with systemic lupus erythematosus (SLE) behave like dendritic cells (DCs), and SLE serum induces healthy monocytes to differentiate into DCs in a type I Interferon (IFN)-dependent manner. Here, we found that these monocytes display significant transcriptional changes, i...

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Publié dans:J Immunol
Auteurs principaux: Rodriguez-Pla, Alicia, Patel, Pinakeen, Maecker, Holden T., Rossello-Urgell, Jose, Baldwin, Nicole, Bennett, Lynda, Cantrell, Victoria, Baisch, Jeanine, Punaro, Marilynn, Gotte, Alisa, Nassi, Lorien, Wright, Tracey, Palucka, Anna Karolina, Banchereau, Jacques, Pascual, Virginia
Format: Artigo
Langue:Inglês
Publié: 2014
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Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5467885/
https://ncbi.nlm.nih.gov/pubmed/24829414
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1301319
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