Systems Scale Interactive Exploration Reveals Quantitative and Qualitative Differences in Response to Influenza and Pneumococcal Vaccines

Systems immunology approaches were employed to investigate innate and adaptive immune responses to influenza and pneumococcal vaccines. These two non-live vaccines show different magnitudes of transcriptional responses at different time points after vaccination. Software solutions were developed to...

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Main Authors: Obermoser, Gerlinde, Presnell, Scott, Domico, Kelly, Xu, Hui, Wang, Yuanyuan, Anguiano, Esperanza, Thompson-Snipes, LuAnn, Ranganathan, Rajaram, Zeitner, Brad, Bjork, Anna, Anderson, David, Speake, Cate, Ruchaud, Emily, Skinner, Jason, Alsina, Laia, Sharma, Mamta, Dutartre, Helene, Cepika, Alma, Israelsson, Elisabeth, Nguyen, Phuong, Nguyen, Quynh-Anh, Harrod, A. Carson, Zurawski, Sandra M., Pascual, Virginia, Ueno, Hideki, Nepom, Gerald T., Quinn, Charlie, Blankenship, Derek, Palucka, Karolina, Banchereau, Jacques, Chaussabel, Damien
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3681204/
https://ncbi.nlm.nih.gov/pubmed/23601689
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.immuni.2012.12.008
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