Systems Scale Interactive Exploration Reveals Quantitative and Qualitative Differences in Response to Influenza and Pneumococcal Vaccines

Systems immunology approaches were employed to investigate innate and adaptive immune responses to influenza and pneumococcal vaccines. These two non-live vaccines show different magnitudes of transcriptional responses at different time points after vaccination. Software solutions were developed to...

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Hauptverfasser: Obermoser, Gerlinde, Presnell, Scott, Domico, Kelly, Xu, Hui, Wang, Yuanyuan, Anguiano, Esperanza, Thompson-Snipes, LuAnn, Ranganathan, Rajaram, Zeitner, Brad, Bjork, Anna, Anderson, David, Speake, Cate, Ruchaud, Emily, Skinner, Jason, Alsina, Laia, Sharma, Mamta, Dutartre, Helene, Cepika, Alma, Israelsson, Elisabeth, Nguyen, Phuong, Nguyen, Quynh-Anh, Harrod, A. Carson, Zurawski, Sandra M., Pascual, Virginia, Ueno, Hideki, Nepom, Gerald T., Quinn, Charlie, Blankenship, Derek, Palucka, Karolina, Banchereau, Jacques, Chaussabel, Damien
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2013
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3681204/
https://ncbi.nlm.nih.gov/pubmed/23601689
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.immuni.2012.12.008
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