Functional Specializations of Human Epidermal Langerhans Cells and CD14(+) Dermal Dendritic Cells

Little is known on the functional differences of the human skin myeloid DC subsets, epidermal CD207(+) Langerhans cells (LCs) and dermal CD14+ DCs. We show that CD14(+) DCs prime CD4(+) T cells into cells that induce naïve B cells to switch isotype and become plasma cells. LCs preferentially induce...

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Bibliographische Detailangaben
Hauptverfasser: Klechevsky, Eynav, Morita, Rimpei, Liu, Maochang, Cao, Yanying, Coquery, Sebastien, Thompson-Snipes, LuAnn, Briere, Francine, Chaussabel, Damien, Zurawski, Gerard, Palucka, A. Karolina, Reiter, Yoram, Banchereau, Jacques, Ueno, Hideki
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2008
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2688399/
https://ncbi.nlm.nih.gov/pubmed/18789730
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.immuni.2008.07.013
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