Immunoglobulin-like transcript receptors on human dermal CD14(+) dendritic cells act as a CD8-antagonist to control cytotoxic T cell priming

Human Langerhans cells (LCs) are highly efficient at priming cytolytic CD8(+) T cells compared with dermal CD14(+) dendritic cells (DCs). Here we show that dermal CD14(+) DCs instead prime a fraction of naïve CD8(+) T cells into cells sharing the properties of type 2 cytokine-secreting CD8(+) T cell...

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Detaylı Bibliyografya
Asıl Yazarlar: Banchereau, Jacques, Zurawski, Sandra, Thompson-Snipes, LuAnn, Blanck, Jean-Philippe, Clayton, Sandra, Munk, Adiel, Cao, Yanying, Wang, Zhiqing, Khandelwal, Sunaina, Hu, Jiancheng, McCoy, William H., Palucka, Karolina A., Reiter, Yoram, Fremont, Daved H., Zurawski, Gerard, Colonna, Marco, Shaw, Andrey S., Klechevsky, Eynav
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: National Academy of Sciences 2012
Konular:
Biological Sciences
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC3503187/
https://ncbi.nlm.nih.gov/pubmed/23112154
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1205785109
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