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Antitumor activity of immunotoxins with T cell receptor-like specificity against human melanoma xenografts

In this study we have explored, the use of Fab-toxin proteins (immunotoxin) to target antigen-specific MHC-peptide complexes of in vitro and in vivo cancer cells. A human phage display library was used to screen for TCR-like antibodies that are highly specific for the peptide melanoma-associated ant...

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Detalhes bibliográficos
Main Authors: Klechevsky, Eynav, Gallegos, Michael, Denkberg, Galit, Palucka, Karolina, Banchereau, Jacques, Cohen, Cyril, Reiter, Yoram
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2728007/
https://ncbi.nlm.nih.gov/pubmed/18676861
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-08-0928
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