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Antitumor activity of immunotoxins with T cell receptor-like specificity against human melanoma xenografts
In this study we have explored, the use of Fab-toxin proteins (immunotoxin) to target antigen-specific MHC-peptide complexes of in vitro and in vivo cancer cells. A human phage display library was used to screen for TCR-like antibodies that are highly specific for the peptide melanoma-associated ant...
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| Autori principali: | , , , , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
2008
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2728007/ https://ncbi.nlm.nih.gov/pubmed/18676861 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-08-0928 |
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