miRNAs Are Essential for the Regulation of the PI3K/AKT/FOXO Pathway and Receptor Editing during B Cell Maturation

B cell development is a tightly regulated process dependent on sequential rearrangements of immunoglobulin loci that encode the antigen receptor. To elucidate the role of microRNAs (miRNAs) in the orchestration of B cell development, we ablated all miRNAs at the earliest stage of B cell development...

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Detaylı Bibliyografya
Yayımlandı:Cell Rep
Asıl Yazarlar: Coffre, Maryaline, Benhamou, David, Rieß, David, Blumenberg, Lili, Snetkova, Valentina, Hines, Marcus J., Chakraborty, Tirtha, Bajwa, Sofia, Jensen, Kari, Chong, Mark M.W., Getu, Lelise, Silverman, Gregg J., Blelloch, Robert, Littman, Dan R., Calado, Dinis, Melamed, Doron, Skok, Jane A., Rajewsky, Klaus, Koralov, Sergei B.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2016
Konular:
Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC5679080/
https://ncbi.nlm.nih.gov/pubmed/27880903
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2016.11.006
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