miR-29 Sustains B Cell Survival and Controls Terminal Differentiation via Regulation of PI3K Signaling

The phosphatidylinositol 3-kinase (PI3K) signaling cascade downstream of the B cell receptor (BCR) signalosome is essential for B cell maturation. Proper signaling strength is maintained through the PI3K negative regulator phosphatase and tensin homolog (PTEN). Although a role for microRNA (miRNA)-d...

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Publicado no:Cell Rep
Main Authors: Hines, Marcus J., Coffre, Maryaline, Mudianto, Tenny, Panduro, Marisella, Wigton, Eric J., Tegla, Cosmin, Osorio-Vasquez, Victoria, Kageyama, Robin, Benhamou, David, Perez, Oriana, Bajwa, Sofia, McManus, Michael T., Ansel, K. Mark, Melamed, Doron, Koralov, Sergei B.
Formato: Artigo
Idioma:Inglês
Publicado em: 2020
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7730937/
https://ncbi.nlm.nih.gov/pubmed/33264610
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2020.108436
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