PTIP chromatin regulator controls development and activation of B cell subsets to license humoral immunity in mice

B cell receptor signaling and downstream NF-κB activity are crucial for the maturation and functionality of all major B cell subsets, yet the molecular players in these signaling events are not fully understood. Here we use several genetically modified mouse models to demonstrate that expression of...

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Bibliografiske detaljer
Udgivet i:Proc Natl Acad Sci U S A
Main Authors: Su, Dan, Vanhee, Stijn, Soria, Rebeca, Gyllenbäck, Elin Jaensson, Starnes, Linda M., Højfeldt, Martina Kubec, Pedersen, Gabriel K., Yuan, Joan, Daniel, Jeremy A.
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 2017
Fag:
PNAS Plus
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5676899/
https://ncbi.nlm.nih.gov/pubmed/29078319
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1707938114
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